PerioChip (chlorhexidine gluconate) 2.5mg is clinically more effective than SRP Alone. Two U.S. multicenter studies showed that patients who received PerioChip after scaling and root planing (SRP) experienced a statistically significant reduction in the depth of their periodontal pockets versus patients who were treated with SRP alone. Approximately twice as many subjects treated with PerioChip+ SRP showed an improvement in pocket depth of 2 mm or more at nine months versus subjects treated with SRP alone: 36% (PerioChip+ SRP) vs. 17% (SRP alone) in Study 94-002 and 25% (PerioChip + SRP) vs. 10% (SRP alone) in Study 94-003).

Sustained Local Delivery of Chlorhexidine in the Treatment of Periodontitis: A Multi-Centre Study

The safety and efficacy of PerioChip were evaluated in a randomized, blinded, multi-centre study of 118 patients with moderate periodontitis. The results of this study show that the treatment of periodontal pockets with CHX as an adjunct to SRP provides a significantly greater improvement in PD compared to the improvement obtained with SRP alone. Another significant improvement was observed in attachment level, at 9 months, in the CHX chip plus SRP treatment compared with SRP alone.